In a May 2020 WBUR review of coronavirus testing results among Boston area homeless service providers, the Mission scored well. The Boston NPR news affiliate compared at least seven agencies providing day and/or evening services to people experiencing homelessness. They found that in larger shelters up to a third of nightly participants tested positive for COVID-19. When Mission staff and guests were tested in April, only one positive result was returned from an employee. Though without symptoms, the employee isolated and tested negative shortly thereafter.
Since March, the Mission has instituted several measures to protect guests and staff against COVID-19, including mandatory face masks, hand washing, disinfecting of surfaces, 6 feet of social distancing, and sleeping changes, like more distance between beds and alternating sleeping guests head to toe.